Suppose it depends on how well the first installment sold. I was under the impression it sold just "okay" so, if that's the case, I suspect they're a bit tentative towards making a sequel.
If they do decide to mind, despite how great AI1 is, I would like to see two changes made in the sequel. I hope they try not to make the story too long like the first one did. It is effectively a steal horror game and towards the end it did start to outstay it's welcome. Particularly around the androids attack area.
The second thing I'd like to see change is the persistency of the alien. I get it's hunting you down and it's great, but there was times where it simply wouldn't go away and it's constant presence made it impossible for you to complete an objective. It sometimes felt you had no other option but to reload and go at the objective from a different way.