I'm feeling optimistic. I think the Creative Assembly and Relic will have solid titles (in fact, Total War: Rome II and Company of Heroes 2 are set in stone for 2013). There will be more digital releases, possibly Skies of Arcadia and Shenmue.
We'll see some more digital Sonic titles, perhaps Sonic 4 Episode III, as well as a new 3D Sonic platformer for all major consoles as well as a 3DS version. Castle of Illusion will likely release to digital platforms soon, and 3DS might get 3D Space Harrier.
Miku for PS3 might be announced for the West, and I'm holding out hope for Yakuza 5 coming late 2013.
On the not-quite-SEGA side of things we might see Bayonetta 2 for the holidays as well as Crimson Dragon on XBLA for the Summer of Arcade event.