It's easier in some ways, harder in others.
If you're on the left side, things are going to be easier because the ghost housing is further away. Therefore, it's wise to start with the right side of the screen first so that there are less ghosts out of the house to contend with and before Inky goes into "Cruise Elroy" mode (in which he is faster than you).
The area above and below the "oo" are the most dangerous places to be, and where you're most likely to be trapped by ghosts. Long stretches of alleyway like that weren't present in the original game, so that makes it a bit more difficult to deal with. You're completely vulnerable as long as you're in there. It's a bit more difficult to reach the fruit sometimes in this game before they disappear, too.
Also, the AI of the ghosts doesn't seem to be the same as it was in the old game. Clyde is all of a sudden aggressively giving chase in this version.
Overall, this is a really super fun game, and I LOVE reading stories about productivity being cut down due to it. ^__^ Hooray Pac-Man! <3