Looking at Wikipedia's '2006 Video games' page, there are a few things that I liked
Dead Rising
Elder Scrolls IV: Oblivion
Elite Beat Agents
Fight Night Round 3
Gears of War
God Hand
Guitar Hero 2
The Legend of Zelda: Twilight Princess
Medieval II: Total War
Okami
OutRun 2006: Coast 2 Coast
Sam and Max Save the World
Splinter Cell: Double Agent (worst game in the series IMO, but still very good)
Virtua Fighter 5
Virtua Tennis 3
Yakuza 2
Others/Expansions/Never played them:Age of Empires III: The WarChiefs
DEFCON
Just Cause
Rome: Total War: Alexander
Rogue Trooper
Saint's Row
WarioWare Smooth Moves (Fuck you, I thought it was fun)
lolwats:
NRA Gun ClubRapeLayRock 'em Sock 'em RobotsOverall, seems pretty solid to me.